Beilstein J. Org. Chem.2012,8, 1271–1278, doi:10.3762/bjoc.8.143
–F bond endo into the ring, and appear to benefit from C–CHF–C angle widening, which relaxes 1,4-H,H transannular interactions.
Keywords: alicyclicchemistry; conformational analysis; cyclododecane; 19F NMR; organo-fluorine chemistry; transannular interactions; Introduction
The conformation of
PDF
Graphical Abstract
Figure 1:
The Dunitz and Shearer structure of cyclododecane (1) [1,2]. There are four endo hydrogens above and fou...
Beilstein J. Org. Chem.2011,7, 222–233, doi:10.3762/bjoc.7.30
and will remain at the forefront of alicyclicchemistry until a stepwise synthesis of C60 is achieved. However, we note en passant that Scott, de Meijere and their colleagues have devised a rational route to C60 from a chlorinated precursor, C60H27Cl3, in which only the final ring closures were
PDF
Graphical Abstract
Figure 1:
Molecular analogues of the Platonic solids.